semaglutide
66% MACE Reduction - Tirzepatide vs Semaglutide Prescription Weight Loss
Tirzepatide cuts major adverse cardiovascular events by 66% more than semaglutide while achieving comparable weight loss. Clinical trials show both drugs produce roughly 12%-13% body-weight reductions, but tirzepatide’s heart-protective effect appears stronger. This difference is shaping prescribing patterns for patients at high cardiometabolic risk. Medical Disclaimer: This article